Number 2 - June
Lufenuron: Potential Promise for Chinchilla Applications?
week in the promotional section of the auction, we are offering
one of the first five 18K Yellow Gold Chinchilla Millennia pendants
to be cast and sold to the public. This piece is the desirable
very low No. 4 in the Limited Edition Series. Don't miss this
opportunity to own one of the first 18K Yellow Gold CM IV sculptures,
starting at only $1 minimum bid. Click
Here to View Item
week we will be listing only the second Black Velvet Royal Persian
Angora ever offered for sale by his breeder, and also the last
Black Velvet Royal Persian Angora to be sold in 2007. To see
this listing, please visit the Chinchillas.com
Auction between June 27th and July 4th.
Potential Promise for Chinchilla Applications?
of the most common problems for domestic chinchilla breeders is the
control and containment of skin fungus. Finding a minimally toxic
and effective treatment for chinchilla fungus would be a great asset
for any chinchilla breeder. Five of the most common treatments for
skin fungus are Desenex, Clotrimazole, Fulvicin, Betadine, and Captan
50. Desenex and Clotrimazole are easy to obtain, relatively inexpensive,
and easy to administer. However, many times they are not completely
effective at eradicating skin fungus. Fulvicin requires a prescription
from a vet, is more expensive, and can potentially cause liver damage,
although it is an effective systemic medication. Betadine is readily
available, easy to administer, and safer to use. Although it will
stain the coat, it tends to be an effective treatment in all but the
most severely afflicted animals. Captan 50 is a plant fungicide that
works extremely well, but it can also be very dangerous for both the
chinchilla and the people exposed to it. I don't recommend its use
on chinchillas for this reason. Of the five treatments mentioned,
only Fulvicin treats systemic infections. The other treatments are
only used to treat afflicted areas topically.
a considerable amount of research two years ago into the best and
safest way to treat a young mare with fungal endometritis (fungal
infection of the uterus), it was suggested by my equine practitioner
that I learn more about the drug lufenuron. It is sold under the brand
name Program to treat dogs and cats for fleas. Although to the best
of my knowledge it is not FDA approved for equine use at this time,
it is used experimentally in the equine industry to treat equine fungal
endometritis. When used on mares, it is not given orally, but infused
directly into the uterus of the mare.
is a benzoylphenyl urea (BPU) derivative and is classified as an
insect development inhibitor that prevents the synthesis, polymerization,
or deposition if chitin.2
Fungal organisms are surrounded by chitin-rich cell walls, and it
is speculated that disruption of this cell wall inhibits fungal
growth. Because BPU derivatives affect chitin production, they are
thought to be safe for use in mammals as mammalian cells lack chitin.
is used most commonly as a once-a-month treatment to provide flea
control for dogs and cats .3
Following oral administration, lufenuron accumulates in adipose
tissue and is slowly released in the blood over time.4
It has also been effective for treatment of dermatomycoses in dogs
and cats.4 On the basis
of results of these reports, it was considered to be a reasonable,
minimally toxic alternative to standard anti-fungal management of
are unaware of any current research or information pertaining to the
use of lufenuron in the chinchilla, and we are not recommending it
be used without proper approval by the FDA and your veterinarian,
but this might be an interesting and potentially important medication
for the chinchilla breeding and veterinary research communities to
look into for treating skin fungus in the chinchilla.
Hess MB, Parker NA, Purswell BJ, Dascanio JD. Use of lufenuron as
a treatment for fungal endometritis in four mares. JAVMA, Vol 221,
No. 2, July 15, 2002; 266-267.
2. Cohen E. Interference with chitin biosynthesis
in insects. In: Wright JE, Retnakaran A, eds. Chitin and benzolphenyl
ureas. Dordrecht, The Netherlands: Dr. W. Junk, 1987; 43-73.
3. Hink WF, Drought DC, Barnett S. Effect of an experimental systemic
compound, CGA-184699, on life stages of the cat flea ( Siphonaptera:
Pulicidae ). J Med Entomol 1991;28:424-427.
4. Ben-Ziony Y, Arzi B. Use of lurenuron for treating fungal infections
of dogs and cats: 297 cases (1997-1999). J Am Vet Med Assoc 2000;217:1510-1513.
Grass is now available in 40 oz packages!
A green, fruity-smelling grass hay with a taste small animals
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